Empathy is the ability to share and understand the emotions of others. It is a construct of multiple components, each of which is associated with its own brain network. New research has found empathy may have a genetic component that affects personality, and cognition, psychiatric (relating to mental illness) conditions. The findings are highlighted in a new study led by researchers at the University of Cambridge, the University Paris Diderot and the Institute Pasteur, and 23andMe.

    Published yesterday inMolecular Psychiatry, the first study found evidence that genes influence our ability to read and understand emotions in others. The team at the Autism Research Centre at the University of Cambridge analyzed data from 89,000 individuals worldwide, the majority of whom were 23andMe customers, who were willing to be researched.

    Participants completed a “Reading the Mind in the Eyes Test”, in which they were shown photos of the area around the eyes and asked to identify one of two possible emotions. This assessed Theory of Mind and the ability to recognize and appreciate another person's mental state. Researchers identified that women with certain genetic variants（变异）on chromosome（染色体）3 performed better, with higher levels of empathy. Interestingly, male performance on the test was not associated with a genetic variant. Overall, women consistently performed better than men, exhibiting higher levels of empathy.

    The genetic variant associated with empathy in women is near the gene LRRN1(Leucine Rich Neuronal 1) on chromosome 3, which is highly active in an area of the human brain. Brain scans have indicated that this section of the brain may play a role in cognition empathy.

    This is also theunprecedentedstudy that relates measures of empathy with variation in the human genome（基因组）. Previous research that has attempted to assess the genetic associations of personality and psychological traits has sometimes been unreliable, due to their small sample size. 23andMe's large data offering enables scientists to gain insight into the biology behind features such as empathy.

    23andMe is committed to furthering such research and approximately 85 percent of customers agrees to allow their de-identified（去识别的）data to be made available for study. By allowing scientists access to its unique and powerful research resource engine, 23andMe helps open up genetics to qualified researchers, providing novel insights into individuals' features, genetic diseases and a variety of other conditions.